Chicken Alfredo Lasagna Roll-Ups Recipe

Oh, I absolutely love how this Chicken Alfredo Lasagna Roll-Ups Recipe brings together two of my favorite dishes—creamy Alfredo pasta and classic lasagna—but with a fun, roll-up twist! It’s such a crowd-pleaser and perfect for when you want comforting Italian flavors without the fuss of layered lasagna. Trust me, once you try these roll-ups, you’ll find they’re easier to prepare and just as satisfying as traditional lasagna.

When I first tried this recipe, I was amazed at how well the creamy Alfredo sauce, tender chicken, and gooey cheese melded together inside those soft noodles. It’s a great dish for weeknight dinners or when you have family over because everyone goes crazy for it. Plus, it reheats beautifully, so you can enjoy leftovers (if they last that long).

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Ingredients You’ll Need

Each ingredient in this Chicken Alfredo Lasagna Roll-Ups Recipe brings its own magic to the table. You’ll want to choose good quality Alfredo sauce and freshly shredded cheeses to make these roll-ups truly shine.

• Lasagna noodles: Look for no-boil or traditional noodles, but make sure to cook them al dente so they roll easily without tearing.
• Alfredo sauce: A creamy, rich jarred sauce works perfectly here—homemade if you have time!
• Shredded cooked chicken: Rotisserie chicken is a great shortcut and adds great flavor.
• Mozzarella cheese: Freshly shredded melts better than pre-shredded with additives.
• Parmesan cheese: Freshly grated Parmesan elevates the cheesy layer with its nutty flavor.
• Garlic powder: Adds that subtle savory note without overpowering the dish.
• Lemon zest: A little brightness to balance out all that creamy goodness.
• Italian seasoning: Classic herb blend that brings the right depth of flavor.
• Fresh parsley (optional): For garnish to add a pop of color and freshness.

Variations

I like to change things up with this Chicken Alfredo Lasagna Roll-Ups Recipe depending on what’s in my fridge or how adventurous I’m feeling. Feel free to experiment—you might just discover your new favorite version!

• Spinach Roll-Ups: I add chopped fresh spinach to the chicken mixture to sneak in some greens while keeping it creamy.
• Spicy Kick: Add red pepper flakes or a dash of hot sauce to the filling for a little heat; my kids prefer it mild, but I love a bit of spice!
• Vegetarian: Swap chicken for sautéed mushrooms and broccoli for a meatless twist that’s still hearty.
• Homemade Sauce: Use homemade Alfredo sauce if you’re up for it—it elevates the dish but the jarred kind is a fantastic time-saver.

How to Make Chicken Alfredo Lasagna Roll-Ups Recipe

Step 1: Prep Your Oven and Dish

First things first, preheat your oven to 350°F. Trust me, getting this step done upfront stops you from scrambling later. Give your casserole dish a light spray with nonstick spray and spread a thin layer of Alfredo sauce on the bottom. This prevents sticking and gives a nice base of creamy flavor.

Step 2: Cook and Cool the Noodles

Cook the lasagna noodles according to the package instructions until they’re al dente—firm but tender. I learned the hard way that overcooking leads to fragile noodles that break when rolling. Drain and rinse them with cold water to stop the cooking process and prevent sticking. Lay them flat on a clean towel or surface so they’re easy to handle.

Step 3: Mix the Filling

In a big bowl, combine half of the Alfredo sauce with shredded chicken, half the mozzarella, half the Parmesan, garlic powder, lemon zest, and Italian seasoning. This mix is where the magic happens—the seasoning and cheeses blend with the creamy sauce and tender chicken to create the perfect filling. Give it a gentle stir to distribute everything evenly.

Step 4: Assemble Your Roll-Ups

Dry any excess water from the noodles with paper towels—that helps the filling stick and keeps things neat. Spread an even layer of the chicken mixture over each noodle, then carefully roll up each one, seam side down, and place them snugly in your prepared casserole dish. This step feels so satisfying when those neat rows start to take shape.

Step 5: Top and Bake

Pour the remaining Alfredo sauce over the rolled noodles, then sprinkle the rest of the mozzarella and Parmesan on top. Cover the dish with foil and bake for 20 minutes, then remove the foil and bake for an additional 10 minutes until the cheese is melted and bubbly. If you want that extra golden, crispy cheese topping, broil for the last 2-3 minutes—but watch it closely!

Step 6: Garnish and Serve

Finish with a sprinkle of fresh chopped parsley for color and a fresh herbal note. Serve warm and watch your friends and family enjoy every creamy, cheesy bite.

How to Serve Chicken Alfredo Lasagna Roll-Ups Recipe

Garnishes

I love to sprinkle fresh parsley on top because it adds such a nice pop of color and a fresh herbal lift to the creamy dish. Sometimes, a little extra grated Parmesan on the plate makes it feel extra indulgent.

Side Dishes

My go-to sides with these Chicken Alfredo Lasagna Roll-Ups are simple green salads tossed with a light vinaigrette or some garlic roasted vegetables. The freshness balances the richness perfectly, and it’s a crowd-pleaser every time!

Creative Ways to Present

For special occasions, I like to bake the roll-ups in a pretty ceramic dish and garnish with edible flowers or finely chopped basil. Laying them in neat rows side by side makes a beautiful presentation that feels like a special treat.

Make Ahead and Storage

Storing Leftovers

I store leftover lasagna roll-ups in an airtight container in the fridge, and they usually last up to 3 days. When I reheat, I add a splash of milk or a little more Alfredo sauce on top to keep them nice and moist.

Freezing

These roll-ups freeze wonderfully. I like to assemble them in a freezer-safe dish, cover tightly with foil, and freeze. When you’re ready to eat, just bake them covered, then uncovered to finish, adding extra time as needed.

Reheating

Reheating is best done in the oven covered with foil at 350°F to prevent drying out—about 15-20 minutes should do. You can finish with a quick broil to revive that baked, melty cheese top.

FAQs

Final Thoughts

This Chicken Alfredo Lasagna Roll-Ups Recipe is one of those dishes I keep coming back to because it’s both comforting and surprisingly easy to put together. Whether you’re cooking for family, entertaining friends, or just craving a delicious meal, these roll-ups never disappoint. I hope you’ll give this a try—you might just find it becoming your new go-to comfort food too!

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